Update of the 2025 and 2026 standard regulatory actions for prospective and retrospective cumulative dietary risk assessment of pesticides in MCRA

Regulatory concern over human exposure to chemical mixtures has intensified, as individuals are continuously exposed to multiple chemical substances from various sources. Historically, the European Food Safety Authority (EFSA) assesses risks based on individual chemicals or expected co‐occurring groups of chemical substances. Recognizing the need for comprehensive methodology, EFSA and the European Commission (EC) initiated in 2021 the gradual implementation of cumulative risk assessment (CRA) for dietary exposure to mixtures of pesticide residues.